Pixmeo OsiriX MD – All CISA Advisories
1. EXECUTIVE SUMMARY
- CVSS v4 9.3
- ATTENTION: Exploitable remotely/low attack complexity
- Vendor: Pixmeo
- Equipment: OsiriX MD
- Vulnerabilities: Use After Free, Cleartext Transmission of Sensitive Information
2. RISK EVALUATION
Successful exploitation of these vulnerabilities could allow an attacker to cause memory corruption, resulting in a denial-of-service condition or to steal credentials.
3. TECHNICAL DETAILS
3.1 AFFECTED PRODUCTS
The following Pixmeo products are affected:
- OsiriX MD: Versions 14.0.1 (Build 2024-02-28) and prior
3.2 VULNERABILITY OVERVIEW
3.2.1 USE AFTER FREE CWE-416
The affected product is vulnerable to a use after free scenario, which could allow an attacker to upload a crafted DICOM file and cause memory corruption leading to a denial-of-service condition.
CVE-2025-27578 has been assigned to this vulnerability. A CVSS v3.1 base score of 7.5 has been calculated; the CVSS vector string is (AV:N/AC:L/PR:N/UI:N/S:U/C:N/I:N/A:H).
A CVSS v4 score has also been calculated for CVE-2025-27578. A base score of 8.7 has been calculated; the CVSS vector string is (AV:N/AC:L/AT:N/PR:N/UI:N/VC:N/VI:N/VA:H/SC:N/SI:N/SA:N).
3.2.2 USE AFTER FREE CWE-416
The affected product is vulnerable to a local use after free scenario, which could allow an attacker to locally import a crafted DICOM file and cause memory corruption or a system crash.
CVE-2025-31946 has been assigned to this vulnerability. A CVSS v3.1 base score of 6.2 has been calculated; the CVSS vector string is (AV:L/AC:L/PR:N/UI:N/S:U/C:N/I:N/A:H).
A CVSS v4 score has also been calculated for CVE-2025-31946. A base score of 6.9 has been calculated; the CVSS vector string is (AV:L/AC:L/AT:N/PR:N/UI:N/VC:N/VI:N/VA:H/SC:N/SI:N/SA:N).
3.2.3 CLEARTEXT TRANSMISSION OF SENSITIVE INFORMATION CWE-319
The Osirix MD Web Portal sends credential information without encryption, which could allow an attacker to steal credentials.
CVE-2025-27720 has been assigned to this vulnerability. A CVSS v3.1 base score of 7.4 has been calculated; the CVSS vector string is (AV:N/AC:H/PR:N/UI:N/S:U/C:H/I:H/A:N).
A CVSS v4 score has also been calculated for CVE-2025-27720. A base score of 9.3 has been calculated; the CVSS vector string is (AV:N/AC:L/AT:N/PR:N/UI:N/VC:H/VI:H/VA:N/SC:N/SI:N/SA:N).
3.3 BACKGROUND
- CRITICAL INFRASTRUCTURE SECTORS: Healthcare and Public Health
- COUNTRIES/AREAS DEPLOYED: Worldwide
- COMPANY HEADQUARTERS LOCATION: Switzerland
3.4 RESEARCHER
Chizuru Toyama of TXOne Networks and Canaan Kao of TXOne Networks reported these vulnerabilities to CISA.
4. MITIGATIONS
Pixmeo recommends users to download the latest version of OsiriX MD.
For additional support regarding OsiriX MD, users should contact Pixmeo directly.
CISA recommends users take defensive measures to minimize the risk of exploitation of this these vulnerabilities, such as:
- Minimize network exposure for all control system devices and/or systems, ensuring they are not accessible from the Internet.
- Locate control system networks and remote devices behind firewalls and isolating them from business networks.
- When remote access is required, use more secure methods, such as Virtual Private Networks (VPNs), recognizing VPNs may have vulnerabilities and should be updated to the most current version available. Also recognize VPN is only as secure as the connected devices.
CISA reminds organizations to perform proper impact analysis and risk assessment prior to deploying defensive measures.
CISA also provides a section for control systems security recommended practices on the ICS webpage on cisa.gov/ics. Several CISA products detailing cyber defense best practices are available for reading and download, including Improving Industrial Control Systems Cybersecurity with Defense-in-Depth Strategies.
CISA encourages organizations to implement recommended cybersecurity strategies for proactive defense of ICS assets.
Additional mitigation guidance and recommended practices are publicly available on the ICS webpage at cisa.gov/ics in the technical information paper, ICS-TIP-12-146-01B–Targeted Cyber Intrusion Detection and Mitigation Strategies.
Organizations observing suspected malicious activity should follow established internal procedures and report findings to CISA for tracking and correlation against other incidents.
CISA also recommends users take the following measures to protect themselves from social engineering attacks:
- Do not click web links or open attachments in unsolicited email messages.
- Refer to Recognizing and Avoiding Email Scams for more information on avoiding email scams.
- Refer to Avoiding Social Engineering and Phishing Attacks for more information on social engineering attacks.
No known public exploitation specifically targeting these vulnerabilities has been reported to CISA at this time.
5. UPDATE HISTORY
- May 8, 2025: Initial Publication
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